AN AUTOSOMAL GENE THAT AFFECTS X CHROMOSOME EXPRESSION AND SEX DETERMINATION IN CAENORHABDITIS ELEGANS
نویسندگان
چکیده
منابع مشابه
Identification of X chromosome regions in Caenorhabditis elegans that contain sex-determination signal elements.
The primary sex-determination signal of Caenorhabditis elegans is the ratio of X chromosomes to sets of autosomes (X/A ratio). This signal coordinately controls both sex determination and X chromosome dosage compensation. To delineate regions of X that contain counted signal elements, we examined the effect on the X/A ratio of changing the dose of specific regions of X, using duplications in XO...
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Tetraploid stocks of Caenorhabditis elegans var. Bristol carrying autosomal and X-linked markers have been produced. Tetraploid hermaphrodites fall into two categories: those that give about 1% male self-progeny and those that give 25 to 40% male self-progeny. The former are basically 4A;4X--four sets of autosomes and four sex chromosomes--and the latter are 4A;3X. Males are 4A;2X. (Diploid her...
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We have identified a new X-linked gene, sdc-2, that controls the hermaphrodite (XX) modes of both sex determination and X chromosome dosage compensation in Caenorhabditis elegans. Mutations in sdc-2 cause phenotypes that appear to result from a shift of both the sex determination and dosage compensation processes in XX animals to the X 0 modes of expression. Twenty-eight independent sdc2 mutati...
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ژورنال
عنوان ژورنال: Genetics
سال: 1984
ISSN: 1943-2631
DOI: 10.1093/genetics/106.1.29